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Optimized Curcumin

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DESCRIPTION
Optimized Curcumin with NeurophenolTM is a unique formula containing 2 clinically supported and trademarked ingredients: Longvida® Optimized Curcumin with extended absorption and bioavailability, and NeurophenolTM proprietary blend of standardized blueberry and grape extracts. Both ingredients support cognitive function in healthy aging adults.
FUNCTIONS
Longvida® Optimized Curcumin, based on patent pending discoveries from UCLA, is a revolutionary new ingredient for healthy brain aging. Longvida®’s Solid Lipid Curcumin Particle (SLCP) Technology meets all three requirements for bioavailability: solubility, permeability, and stability, as evidenced by therapeutic levels of free curcumin detected in the bloodstream and target tissues. The SLCP technology formulation precisely preserves curcumin particles in a solid lipid base in a way that preserves and protects the curcumin from the harsh environment of the stomach, and allows it to dissolve at the optimal point for absorption in the GI tract. The end result permits maximal absorption of the active free form of curcumin.
Curcumin is insoluble in water at neutral and acidic pH, undergoes rapid glucuronidation, and is generally thought to be poorly bioavailable and rapidly excreted. Several human pharmacokinetic studies have only detected curcumin in blood in the inactive glucuronide form. Free curcumin is the only form that has been shown to pass the blood brain barrier.
Longvida® Curcumin is supported by more than a dozen bioavailability studies showing extended absorption and 65 times more bioavailability than typical curcuminoids, with a half-life of 7 hours, versus 2 hours for phospholipid curcumin and 0-1 hours for unformulated curcumin.

Optimized Curcumin

Optimized Curcumin Image

DESCRIPTION
Optimized Curcumin with NeurophenolTM is a unique formula containing 2 clinically supported and trademarked ingredients: Longvida® Optimized Curcumin with extended absorption and bioavailability, and NeurophenolTM proprietary blend of standardized blueberry and grape extracts. Both ingredients support cognitive function in healthy aging adults.
FUNCTIONS
Longvida® Optimized Curcumin, based on patent pending discoveries from UCLA, is a revolutionary new ingredient for healthy brain aging. Longvida®’s Solid Lipid Curcumin Particle (SLCP) Technology meets all three requirements for bioavailability: solubility, permeability, and stability, as evidenced by therapeutic levels of free curcumin detected in the bloodstream and target tissues. The SLCP technology formulation precisely preserves curcumin particles in a solid lipid base in a way that preserves and protects the curcumin from the harsh environment of the stomach, and allows it to dissolve at the optimal point for absorption in the GI tract. The end result permits maximal absorption of the active free form of curcumin.
Curcumin is insoluble in water at neutral and acidic pH, undergoes rapid glucuronidation, and is generally thought to be poorly bioavailable and rapidly excreted. Several human pharmacokinetic studies have only detected curcumin in blood in the inactive glucuronide form. Free curcumin is the only form that has been shown to pass the blood brain barrier.
Longvida® Curcumin is supported by more than a dozen bioavailability studies showing extended absorption and 65 times more bioavailability than typical curcuminoids, with a half-life of 7 hours, versus 2 hours for phospholipid curcumin and 0-1 hours for unformulated curcumin.